Jan 23, 2023 · This page gives you the facts and mechanisms for the reduction of carbonyl compounds (specifically aldehydes and ketones) using sodium tetrahydridoborate (sodium borohydride) as the reducing agent.

Jan 23, 2023 · This page looks at the reduction of aldehydes and ketones by two similar reducing agents - lithium tetrahydridoaluminate(III) (also known as lithium aluminium hydride) and sodium tetrahydridoborate(…

This page looks at the reduction of aldehydes and ketones by two similar reducing agents - lithium tetrahydridoaluminate(III) (also known as lithium aluminium hydride) and sodium tetrahydridoborate(III) (sodium borohydride).

Aldehydes produce 1º-alcohols and ketones produce 2º-alcohols. In metal hydrides reductions the resulting alkoxide salts are insoluble and need to be hydrolyzed (with care) before the alcohol product can be isolated.

Aug 18, 2017 · On paper, NaBH 4 and LiAlH 4 are equally effective in performing the reduction of an aldehyde or ketone to an alcohol. In practice, LiAlH 4 is a much stronger reductant that will also reduce esters and carboxylic acids to alcohols.

NaBH 4 Reduction of Aldehydes and Ketones – The Mechanism . Sodium borohydride reduces aldehydes and ketones by a similar mechanism with some important differences that we need to mention. First, NaBH 4 is not so reactive and the reaction is usually carried out in protic solvents such as ethanol or methanol. The solvent has two functions here:

The main difference is that reduction of aldehydes or ketones generally requires a much higher pressure of hydrogen gas. Thus, you could reduce a double bond of an alkene without touching the double bond of a ketone or an aldehyde.

Aldehydes and ketones can undergo reduction process for the formation of either primary alcohol or secondary alcohol with the help of reagents, sodium borohydride (NaBH 4) or lithium aluminium hydride (LiAlH 4).

Reacts with carboxylic acids, esters, lactones, anhydrides, amides and nitriles, converting them into alcohols and amines. Ketones, aldehydes, epoxides, alkyl halides are also reduced with lithium aluminium hydride. Reduces aldehydes and ketones to corresponding alcohols.

Alcohols can be prepared from carbonyl compounds such as aldehydes, ketones, esters, acid chlorides and even carboxylic acids by hydride reductions. These reductions are a result of a net addition of two hydrogen atoms to the C=O bond: