In S. Cerevisiae, meiotic stress granules (SGs) form at temperatures ~10°C lower than those in mitosis, seeded by the meiosis-specific RNA-binding protein Rim4. These SGs halt meiosis and ...

Protein–protein interaction networks are the networks of protein complexes formed by biochemical events and/or electrostatic forces and that serve a distinct biological function as a complex ...

Novartis has been building a position in protein degraders - for example, signing a $1.3 billion alliance with Dunad Therapeutics in 2021 - but ARV-766 will be its first clinical-stage programme.