Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

Researchers have revealed the structure of U11 snRNP – one of the five subunits of the minor spliceosome, which initiates the intron selection process.

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

The mRNA splicing is a multi-step process catalyzed by various small nuclear ribonucleoprotein (snRNP) particles that dynamically assemble, along with other proteins, in a macromolecular machinery ...

RNPs include, but are not necessarily limited to, ribosomes, spliceosomes, small nuclear RNPs (snRNP), small nucleolar RNPs(snoRNPs ... Keywords: ribosome, spliceosome, telomerase, small nulcear ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA.

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA.