Now, researchers from Kyushu University have revealed that the smallest known protein-based tRNA-processing enzyme, called ...

(a) Design of an artificial guide RNA (Act-BP-guide) targeting ACT1 pre-mRNA for 2′-O-methylation. Only the guide sequence is shown. Box C, box D and the terminal stem of Act-BP-guide as well as ...

When these pre-mRNA sequences undergo constitutive splicing, the removal of introns is followed by the joining of exons in their DNA-corresponding order. Alternative splicing deviates from this ...

Researchers report this month that MALAT1, a long non-coding RNA that is implicated in certain cancers, regulates pre-mRNA splicing -- a critical step in the earliest stage of protein production.

Professor Hirohide Saito and his research team have developed a new microRNA-responsive hybrid mRNA switch, enabling precise, ...

One of mRNA’s greatest advantages is the ability to rapidly iterate and optimize sequences, accelerating drug discovery and development. Advances in cell-free gene synthesis and in vitro transcription ...

As scientists develop and manufacture novel mRNA therapeutics, they must find technologies that help analyze their drug products on a large scale. Direct mRNA sequence mapping with mass spectrometry ...