To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian ...

Compared to the standard shot, the mRNA vaccine had an overall vaccine efficacy that was 26.6 percent higher, and 27.4 ...

A more effective vaccine technology may be on the horizon. In a new study in mice, researchers from the University of ...

A research team from The University of Osaka and the Institute of Science Tokyo has developed a class of mRNA medicines that ...

Researchers develop a self-regulating mRNA medicine that adjusts protein production based on disease-related signals.

Scientists have discovered the internal shape of tiny drug-delivery particles – called lipid nanoparticles – has a big impact ...

When a stop codon in the mRNA reaches the A site of the ribosome at the end of the elongation phase of protein synthesis, translocational release factors (RF1, RF2 and RF3 in bacteria) catalyse ...

This valuable manuscript investigates the localisation of nutrient receptors in bloodstream stage trypanosomes, with implications for both nutrient uptake and immune evasion. Results after direct ...

BioNTech has agreed to acquire mRNA specialist CureVac for approximately $1.25bn, as the big pharma company amps up its strategy to offer cancer treatments using the modality. According to the deal, ...

By comparing the observations of the genes with the expected ENC curves based on GC3, it is possible to make a preliminary judgment on the extent of the effect of mutational stress on codon usage ...