Quality assurance in the cell: Preventing defective protein blueprints
Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger ...
eLife12d
Generative modeling for RNA splicing predictions and design
Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...
Technology Networks4d
Structural Insights Into the Cell's Quality Control Machinery
They succeeded once they were able to isolate the splicing complexes of the fungus that were in the midst of quality control ...
Scientists Discover How To Reactivate Cancer’s Dormant “Kill Switch”
The discovery could pave the way for a groundbreaking RNA-based multi-cancer treatment. Alternative RNA splicing functions ...
Scientists discover how to reactivate cancer's molecular 'kill switch'
Alternative RNA splicing is like a movie editor cutting and rearranging scenes from the same footage to create different ...
Asian News International on MSN14d
New study reveals a simple genetic approach to tackle aggressive cancers
Scientists from The Jackson Laboratory and UConn Health found that cancer cells disrupt poison exons, leading to tumor growth ...
GlobalData on MSN4d
Wave Life Sciences unveils Phase II data for DMD therapy, WVE-N531
Wave Life Sciences’ Phase II open-label trial investigating its disease-modifying drug for boys living with Duchenne Muscular ...
Discover Magazine on MSN12d
Triggering Cancer Cells To Self-Destruct Could Help Tumors to Shrink
Natural "off switch" could slow or even reverse the growth of aggressive tumors.