Post position matters quite a bit at the Kentucky Derby. Horses in the earlier post positions have traditionally performed better than horses in the later post positions at the event. The fifth post position has resulted in the most wins at the Kentucky Derby, with 10 horses winning from that slot during the race's history.

The Kentucky Derby will start the 2025 competition for horse racing's Triple Crown with a field of 19 horses set to race in the annual Run for the Roses.