Alternative splicing, a clever way a cell generates many different variations of messenger RNAs — single-stranded RNAs involved in protein synthesis — and proteins from the same stretch of DNA, plays ...

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs -- single-stranded RNAs involved in protein synthesis -- and proteins from the same stretch of DNA ...

Identifying splice sites is also important in annotating genomes, which involves identifying which parts of our DNA are functional and what roles they play in the body. One familiar application of ...

During the first step of converting genetic information into functional proteins, cells transcribe the double-stranded helix ...

SPLICE-neo is the first tool to comprehensively identify and prioritize splicing neoantigens from both DNA splice-site mutations and de novo RNA aberrant splicings. There are two major advances of ...

But when there is a splicing mutation, nucleoids at the splice site are inserted or deleted. These splicing mutations are linked to a range of genetic alterations in AML, with 20 percent of the cases ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are ...

The spliceosome and Group II introns are believed to share a common ancestor that was responsible for spreading introns throughout the genome, but while Group II introns can splice themselves out of ...