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Recently, a cryo-EM reconstruction yielded major insights into the architecture of a 13-subunit U11 snRNP revealing the structure of a core complex comprising 5 interacting minor spliceosome proteins ...

Biological sciences encompasses all the divisions of natural sciences examining various aspects of vital processes. The concept includes anatomy, physiology, cell biology, biochemistry and ...

Ten Indian American scientists were honored for their outstanding contributions in cancer research by the (SAASCR).

Synopsis Disrupting the expression of the minor spliceosome component RNPC3 reduces the growth of oncogene-driven cancer cells in a broad spectrum of tumours. Targeting the minor spliceosome may ...

Sudemycin K, a derivative that replaces the pharmacophore’s oxycarbonyl by an amide group, displays improved potency as an inhibitor of cancer cell proliferation, as a regulator of alternative ...