This study shows that RNA decay rather than the presence of premature termination codons triggers a TA-like response.

Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...

For natural cells, the so-called central dogma of molecular biology describes how protein synthesis occurs through transcription and translation of genetic information in the cell. In the process, DNA ...

This study provides proof-of-principle data for the use of trained immunity to modulate macrophage interactions with tumours. The study makes a valuable contribution to the field of trained immunity.

RNA viruses are diverse ... Viral RdRp is the key player in the synthesis of all these RNAs. The process usually requires forming a transcription and replication complex (RTC) containing viral ...

Heidelberg biochemists and structural biologists from Shanghai unravel the roles of two key regulatory factors in mRNA ...

Scientists at Oak Ridge National Laboratory have developed the first-ever method of detecting ribonucleic acid, or RNA, ...

Scientists found that pseudouridine helps small RNAs pass on traits and avoid immune detection, offering clues for future RNA ...

Unlike animals, plants do not possess an adaptive immune system with antibodies or T cells to fight viral infections. Instead ...