Learn how cell-free protein synthesis helps researchers overcome the challenges of traditional membrane protein production ...

A new study reveals that blocking ribosomal RNA production rewires cancer cell behavior and could help treat genetically ...

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences ...

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences uncovered a new tumor-suppressive response that could lead to novel ...

Barcelona-based genetic medicines company SpliceBio has raised $135 million in a series B round to back its novel protein-splicing drug delivery system, the biotech announced Wednesday. The money will ...

We observed the same splicing switch if de novo protein synthesis was inhibited by the presence of cycloheximide (Fig. 1E; Appendix Fig. S 1C). These experiments show a fast and transient splicing ...

1 Introduction Inteins have become powerful tools in synthetic biology, biotechnology, and biochemistry. These proteins were discovered by Bowman et al. (1988), and the mechanism of intein trans ...

The team also discovered that in the absence of hnRNPM, cryptic splicing can form double stranded RNA (dsRNA), which is known to trigger interferon immune responses. "Tumors with low hnRNPM show ...

When the genetic code is transcribed into RNA for protein synthesis, alternative splicing can lead to the production of different transcripts from the same gene, depending on the selected genetic ...

When the genetic code is transcribed into RNA for protein synthesis, "alternative splicing" can occur. This means that different transcripts can be produced from the same gene, depending on the ...