A new study reveals that blocking ribosomal RNA production rewires cancer cell behavior and could help treat genetically ...

The disruption causes a protein imbalance that can result in mis-splicing of multiple genes involved in brain function, and may explain why some of the social and behavioral outcomes of ASD ...

Modifying RNA through either splicing or editing is a fundamental biological process for creating protein diversity from the same genetic code. Developing novel chemical biology tools for RNA editing ...

Biologists have discovered a new type of RNA-splicing regulation that helps to determine which protein-coding exons will be included in messenger RNA transcripts.

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...

JOURNAL NAME: American Journal of Molecular Biology, Vol.15 No.1, January 24, 2025 ABSTRACT: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a member of the proprotein convertase (PCs) family ...

Home | Biology | Nucleic acids and proteins | Transcription and translation Transcription and translation Protein synthesis is made up of two stages: transcription and translation. Transcription and ...

Johns Hopkins researchers have developed a powerful new AI tool called Splam that can identify where splicing occurs in genes—an advance that could help scientists analyze genetic data with greater ...

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

By identifying shared splicing neoantigens present in up to 90% of cancer patients, SNAF presents new therapeutic targets and expands understanding of cancer biology ...