Scientists at the UCLA Health Jonsson Comprehensive Cancer Center and the University of Toronto have revealed how a tiny ...

Synthetic Biology is advancing the use of microorganisms as cancer therapies, with scientists engineering bacteria to boost antitumor immunity and deliver ...

Drugs and other treatments can be quite effective at killing cancer cells, yet many fall short as they struggle to penetrate ...

Despite the high incidence of brain metastasis after resection of non-small cell lung cancer (NSCLC), the National Comprehensive Cancer Network guidelines do not recommend central nervous system (CNS) ...

In addition to exporting materials out of the nucleus, the protein, called Exportin-1 (also called Xpo1 or Crm1), seems to play a role in promoting gene transcription, the process that creates RNA ...

The method triggers immune responses that inhibit melanoma, triple-negative breast cancer, lung carcinoma, and ovarian cancer. Cancer treatment vaccines have been in development since 2010, when the ...

Proper splicing requires efficient spliceosome assembly ... A mechanistic study reveals that RBPMS suppresses bladder cancer cell migration by regulating alternative splicing of ANKRD10, which ...

We characterized back-splicing cis- and trans-elements, and found viral circRNAs resistant to spliceosome perturbation and lacking canonical splice donor-acceptors. Subsequent loss-of-function studies ...

Overriding the "Off Switch" Cells function through an intricate network of proteins, each designed for specific tasks like ...

Cancer Discovery publishes high-impact articles featuring major advances in research and clinical trials. Topics span the spectrum of cancer research and medicine from the laboratory to the clinic to ...

Prostate cancer (PCa) is the second most common male cancer and about ... miRNA located within of mirtrons and are associated with spliceosome-dependent mechanisms. After, the mature miRNA produced by ...

A renowned medical school whose faculty helped treat a young cancer survivor honored this week by President Donald Trump is facing potentially devastating funding cuts because of the White House.