This is even more true for molecular machines that are scarce in cells, like the minor spliceosome. "One of the biggest challenges in studying this complex was to figure out how to selectively ...

This is even more true for molecular machines that are scarce in cells, like the minor spliceosome. "One of the biggest challenges in studying this complex was to figure out how to selectively ...

Now, Hiten Madhani of the University of California, San Francisco, and colleagues have implicated the spliceosome, a molecular complex that excises introns from pre-messenger RNAs (pre-mRNAs), in ...

This process is controlled by a large protein-RNA complex called the spliceosome. MIT biologists have now discovered a new layer of regulation that helps to determine which sites on the messenger ...

For many eukaryotic introns, splicing is done in a series of reactions which are catalyzed by the spliceosome, a complex of small nuclear ribonucleoproteins (snRNPs) and associated proteins ...

The vast majority of introns are removed by the major spliceosome, a 60 S complex containing five small nuclear RNAs (snRNAs: U1, U2, U4, U5 and U6) and well over 50 different polypeptides (Fig.

Biologists have discovered a new type of RNA-splicing regulation that helps to determine which protein-coding exons will be included in messenger RNA transcripts. RNA splicing is a cellular ...