In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell select this information? A large molecular machine called the spliceosome ...

Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...

and U5 snRNPs). How exactly these blocks assemble to build the minor spliceosome and help it fulfil its function remains elusive. Structures of large molecular machines are notoriously difficult ...