LUC7 proteins define two major classes of 5′ splice sites in animals and plants. Nature Communications, 2025; 16 (1) DOI: 10.1038/s41467-025-56577-4 ...

The major spliceosome consists of five subunits, U1, U2, U4, U6, and U5 small nuclear ribonucleoprotein particles (snRNPs, read "snurps") – and about 150 proteins, involved in different stages ...

Heidelberg University. "Spliceosome: How cells avoid errors when manufacturing mRNA." ScienceDaily. ScienceDaily, 7 February 2025. <www.sciencedaily.com / releases / 2025 / 02 / 250207122612.htm>.

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing ...

What is the best soil for indoor plants? “Choosing the right soil for your indoor plants depends on your watering habits and the overall humidity in your space,” says Victor Castro, a plant ...

After a decade of work, scientists have completed a molecular model of the human spliceosome, an incredibly complex cellular machine. When an active gene is expressed in a cell, it is transcribed into ...

The spliceosome is the collection of 150 different proteins and five small RNA molecules which orchestrate the editing process, but until now, the specific roles of its numerous components were not ...

The spliceosome edits genetic messages transcribed from DNA, allowing cells to create different versions of a protein from a single gene. The vast majority of human genes – more than nine in ten ...

First Spliceosome Blueprint Reveals Complex Interplay, Uncovers Drug Targets October 31, 2024 ...

Pre-mRNA splicing, executed by spliceosomes, has been extensively studied in yeast and humans, but the structural diversity of spliceosomes in other species, such as plants, remains less understood.