who has been working on pre-mRNA splicing machinery for more than 15 years, first decided to focus on the minor spliceosome seven years ago. When the Galej Group started the project, little was ...

EMBL Grenoble Group Leader Wojciech Galej, who has been working on pre-mRNA splicing machinery for more than 15 years, first decided to focus on the minor spliceosome seven years ago – a project ...

The spliceosome, which forms on introns ... "What we see is that humans and plants tend to have more complex splicing machinery, with additional components that can regulate different introns ...

We study minor spliceosome which is a parallel pre-mRNA splicing machinery in the cells of most metazoan organisms. Our main aim is to investigate mechanism and regulation of this nuclear machinery, ...

These sequences, which help position the splicing apparatus, are found in the exons of genes and bind proteins that help recruit splicing machinery to the correct site. Most splicing occurs ...

The RNA quality control machinery directs the degradation of ... Proper splicing requires efficient spliceosome assembly. Here the authors reveal that zinc finger protein 207 interacts with ...

The spliceosome, which forms on introns ... about these highly conserved molecular processes." "Complex splicing machinery" Previous work has shown that mutation or deletion of one of the LUC7 ...