Viral circRNAs lack canonical spliceosome cis-elements and are unaffected by perturbation of the spliceosome or lariat-debranching enzyme. Loss-of-function studies targeting human RNA ligases reduced ...

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Baylor walked into the CU Events Center on Saturday on a low note. The Bears had dropped two straight games in convincing fashion since losing starting center Josh Ojianwuna to a season-ending knee ...

Get Instant Summarized Text (Gist) A new regulatory mechanism in RNA splicing has been identified, involving LUC7 proteins that influence spliceosome targeting of specific 5' splice sites. This ...

Biologists have discovered a new type of RNA-splicing regulation that helps to determine which protein-coding exons will be included in messenger RNA transcripts. RNA splicing is a cellular ...

Once again, Langston Love sat on the trainer’s table, wincing. It was the encore to a setlist he never wanted to play. Over the past four seasons, Love has taken a personal odyssey through injury ...

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GENETIC researchers in Barcelona have reached a historic milestone, creating the very first map of the spliceosome. A key part of interpreting DNA, the spliceosome helps cells to interpret and ...

The fit between a splice site and the spliceosome components that bind it influences splicing activity. Strong splice sites closely match consensus sequences and are efficiently recognized by the ...