For many eukaryotic introns, splicing is done in a series of reactions which are catalyzed by the spliceosome, a complex of small nuclear ribonucleoproteins (snRNPs) and associated proteins ...

The results come from the phase 3 SCIENCE trial (NCT05244798), which included 146 patients with previously untreated, locally advanced ESCC. The patients were randomly assigned to receive 1 of 3 ...

177Lu-PNT6555 is under clinical development by Eli Lilly and Co and currently in Phase I for Esophageal Squamous Cell Carcinoma (ESCC). According to GlobalData, Phase I drugs for Esophageal Squamous ...

Get Instant Summarized Text (Gist) The first total synthesis of inaoside A, a compound from the mushroom Laetiporus cremeiporus, has been achieved. This synthesis, using α-selective Schmidt ...

GENETIC researchers in Barcelona have reached a historic milestone, creating the very first map of the spliceosome. A key part of interpreting DNA, the spliceosome helps cells to interpret and ...