A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA.

Spliceosomes are large and dynamic RNA-protein complexes. The major spliceosome consists of five subunits, U1, U2, U4, U6, and U5 small nuclear ribonucleoprotein particles (snRNPs, read “snurps”) – ...

In addition, it was shown that insulin influences the function of the so-called spliceosome complex, a key regulatory element of gene regulation. This suggests that the hormone insulin performs ...

Plants survive cold by adjusting at cellular level. Scientists discovered that the PORCUPINE protein helps plants adapt to ...

On the other hand, this protein is part of the spliceosome, a molecular complex that modifies RNA before it is translated into proteins. Dikaya and her colleagues also identified several genes ...

After a gene is transcribed into a pre-mRNA, specific exonic sequences are retained and intronic regions are removed by a macromolecular complex known as the spliceosome. Exons can also be ...