In myasthenia gravis, complement plays a big role in what happens to the muscle end of the neuromuscular junction, explains ...

Chromatin is the DNA-protein complex that, when condensed, forms our chromosomes. The virus then reshapes the architecture of the chromatin, similar to folding origami, to bring itself into contact ...

Researchers at the Centre for Genomic Regulation (CRG) in Barcelona, a BIST Community centre, have created the first blueprint of the human spliceosome, the most complex and intricate molecular ...

“The spliceosome is the complex molecular machinery that sequentially assembles on eukaryotic messenger RNA precursors to remove introns (pre-mRNA splicing), a physiologically regulated process ...

The C complex is remodeled into the step II catalytically activated spliceosome (C * complex), representing a functional state poised and awaiting the exon ligation reaction (Zhan et al, 2022). In the ...

The human genome has hundreds of thousands of introns, about 7 or 8 per gene, and each is removed by a specialized RNA protein complex called the "spliceosome" that cuts out all the introns and ...

Feb. 7, 2025 — A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into ...