Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger ...

Defining where to start cutting out the introns is just the first step in the spliceosome's complex assembly pathway. At least a dozen other steps are needed before the splicing reaction concludes.

Proper splicing requires efficient spliceosome assembly. Here the authors reveal that zinc finger protein 207 interacts with the U1 small nuclear ribonucleoprotein to accelerate spliceosome ...

Aided by two molecular control factors, the spliceosome rejects pre-mRNA that ... the cutting and assembly of mature messenger RNA – a prerequisite for protein synthesis in the cell.