A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA.

How does the cell select this information? A large molecular machine called the spliceosome continuously separates the coding and non-coding regions of our genes—and it's doing this even as you ...

“Understanding why this is the case, understanding how these fluctuations in temperature are sensed and how those signals are transduced into sort of spliceosome function is certainly something that's ...

Y14 — a protein that binds RNA in a spliceosome-dependent manner and ... the mRNA was cleaved in a sequence-specific manner. An anti-Y14 antibody was then used to show that only specific RNA ...

a spliceosome component, as well as RNA helicase, and immortalization-upregulated nuclear proteins. Antibody production using cDNA immunization: When an expression vector carrying human full-length ...