Phys.org on MSN8d
The spliceosome: An atomic-level look into how cells avoid errors when manufacturing mRNA
is correctly assembled into mature mRNA. Splicing is a basic requirement for producing proteins that fulfill an organism's ...
The minor spliceosome: Researchers reveal new structural insights into an essential RNA-protein complex
In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
Hosted on MSN1mon
Genes spatially organize for efficient mRNA splicing, study shows
More information: Prashant Bhat et al, Genome organization around nuclear speckles drives mRNA splicing efficiency, Nature (2024). DOI: 10.1038/s41586-024-07429-6 Provided by California Institute ...
The Scientist4mon
All About Alternative Splicing
Research into splicing mechanisms and patterns is essential for decerning fundamental biological principles, as well as clarifying the molecular basis of many diseases and developing new therapies. 2 ...
Healio1d
FDA approves Evrysdi tablets for spinal muscular atrophy
The FDA has approved Evrysdi in tablet form for patients with spinal muscular atrophy aged 2 years and older who weigh more ...
How Cells Avoid Errors When Manufacturing mRNA
A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...
AZoLifeSciences on MSN1d
Understanding the Complex Architecture of the Minor Spliceosome
In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
Armed robbery in Revesby8d
Spliceosome: Cells' Error-Free MRNA Production Explained
A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...
The American Journal of Managed Care2d
Risdiplam Tablet for Spinal Muscular Atrophy Receives FDA Approval
The 5 mg risdiplam tablet provides the same efficacy and safety for spinal muscular atrophy as the currently available oral ...
EurekAlert!9d
Deciphering the regulatory programs of RNA binding proteins in rheumatoid arthritis through single-cell transcriptome analysis
Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...
News Medical on MSN8d
Dysregulation of RNA-binding proteins in rheumatoid arthritis and osteoarthritis
Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...
News Medical on MSN6d
Alternative RNA Splicing in Cardiac Diseases
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