Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...

Medically reviewed by Soma Mandal, MD Petechiae are tiny red, purple, or brown spots on your skin, inside of your mouth, or ...

Stimulating platelet production with romiplostim is an effective strategy for managing patients with ITP. Thrombocytopenias can be caused by increased platelet destruction, decreased platelet ...

Rituximab, a monoclonal antibody directed against the CD20 molecule found on pre-B cells and mature B cells (but not on plasma cells), was introduced in the late 1990s for the treatment of non ...

B-cell prolymphocytic leukemia (B-PLL) is a rare, aggressive type of leukemia that progresses rapidly. People with B-PLL typically have a less favorable outlook. However, new targeted treatments ...

He was bleeding internally, his spleen had ruptured, she did a splenectomy,” Wilder explained. In the doctor notes recorded on June 15, 2023, it clearly states a splenectomy was performed at 2 a ...

Dana Schulz is an experienced editor, writer, and content strategist who is just as likely to be crunching the ...

As COVID-19 began to surge five years ago, no one knew what to expect. Neither did the immune system. Confronted with a new virus, humanity was immunologically naive. The emergence of SARS-CoV-2 ...

Study unveils key immune cells found to boost cancer treatment success in acute myeloid leukemia New computational tool aims to identify immune responses to cellular therapy in AML treatments Date ...

A man known as "The Truck Stop Serial Killer" was convicted Wednesday in the 2007 murder of an Indianapolis woman. Bruce Mendenhall has now been found guilty of three murders, and he remains a ...