The transplantation of HMDMs via the spleen into an immunocompromised mouse model of liver fibrosis resulted in a regression of collagen and a reduction in markers of liver injury. These findings ...

Cystic fibrosis (CF) treatment typically involves procedures and medications that help clear the airways. Other treatments may include antibiotics, pancreatic enzymes, a high-calorie diet, and ...

YAP/TAZ are Crucial Regulator of Macrophage-mediated Pulmonary Inflammation and Fibrosis after Bleomycin-induced Injury. European Respiratory Journal , 2025; 2301544 DOI: 10.1183/13993003.01544 ...

How Drugs Get on the Pipeline Explore the Pipeline Find a Clinical Trial Help blaze a trail to better treatments and a cure for cystic fibrosis. As a clinical trial volunteer, you are paving the way ...

TGF-β (transforming growth factor-β) is well identified as a central mediator in renal fibrosis. TGF-β initiates canonical and non-canonical pathways to exert multiple biological effects. Among them, ...