Nature2mon
Non-coding RNAs: lessons from the small nuclear and small nucleolar RNAs
For example, C/D and H/ACA RNP function seems to require the adjustment of the conformation of the guide RNA by the binding of the auxiliary protein L7Ae. The study of small nuclear ...
Nature8mon
Specialization and evolution of endogenous small RNA pathways
As small RNA populations from different species throughout ... The duplex is paired such that each 3′ end contains a 2-nucleotide overhang. NLS, nuclear localization signal.
Howard Hughes Medical Institute3mon
A Portrait of RNA Polymerase
It can also create a few other types of RNA, including small nuclear RNA (which forms complexes with other proteins to process mRNA) and microRNA (which regulates the translation process). An RNA ...
The minor spliceosome: Researchers reveal new structural insights into an essential RNA-protein complex
In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
mskcc.org6y
RNA Decay
the RNA exosome. The exosome also participates in processing small nucleolar and small nuclear RNAs (snoRNAs, snRNAs) and ribosomal RNAs (rRNAs) and degradation of many non-coding RNAs including those ...
techexplorist1d
New type of control over RNA splicing discovered
RNA splicing is crucial for gene expression. After DNA is copied into messenger RNA (mRNA), noncoding parts called introns are removed, and the coding parts are spliced together.
Armed robbery in Revesby15d
RNA Binding Protein Role in Arthritis Unveiled via SC Transcriptomics
Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of RNA-binding proteins (RBPs), which are critical for alternative ...
EurekAlert!14d
Peri-centrosomal localization of small interfering RNAs in C. elegans
Centrosomes are nonmembrane organelles and responsible for microtubule nucleation and organization. Centrosomal RNAs have been identified in diverse model systems and are known to regulate gene ...
KSL1mon
Hill Air Force Base could get small nuclear reactor as soon as 2028
(Photo: Radiant, U.S. Department of Energy) The nuclear reactors in question are small enough to be delivered on a truck or a C-17 aircraft. "Our system lasts for five years, and then you shut it ...
EurekAlert!16d
Deciphering the regulatory programs of RNA binding proteins in rheumatoid arthritis through single-cell transcriptome analysis
Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...
News Medical on MSN15d
Dysregulation of RNA-binding proteins in rheumatoid arthritis and osteoarthritis
Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...