Cells have a natural editing system that allows them to rearrange genetic instructions to create different proteins from the ...

RNA splicing is a modification of the nascent ... and associated proteins, but there are also self-splicing introns. By using cryo-EM and biochemical assays, Loeff et al. reveal the mechanistic ...

Other ribozymes include self-splicing introns and the RNA component of the enzyme telomerase. Non-coding RNA molecules, such as miRNAs (miRNAs) and long non-coding RNAs (lncRNAs), play essential roles ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns ...

RBP splicing factors are sequence-specific, binding to their cognate sequence motifs like a lock and key. “Because the binding pocket of the RBP matches the sequence motif, the RBP binds to the ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical ...

Overview of RNA repair – There is an emerging appreciation of the existence of “RNA repair” pathways that rely on RNA ligases to maintain or manipulate RNA structure in response to purposeful RNA ...

"There is a lot of evidence that the RNA parts of the spliceosome ... many researchers have theorized that when the process of self-splicing became too inefficient for Group II introns to reliably ...