Ribosomes are the sites in a cell in which protein synthesis takes place. Cells have many ribosomes, and the exact number depends on how active a particular cell is in synthesizing proteins.

During translation, ribosomes can pause on the nucleic acid. Researchers showed that collisions from incoming proteins get ...

At this point, translation must be terminated, and the nascent protein must be released from the mRNA and ribosome. Termination of Translation There are three termination codons that are employed ...

During their study, they found that ribosomes exhibit cooperative behavior when encountering difficulties in the cell. The technique offers new insights into protein production and mRNA translation ...

In frame translation initiation sites within coding sequences drive the expression of N-terminally truncated proteoforms.

A novel microscopy method has been created by researchers from the Tanenbaum group at the Hubrecht Institute to view the activity of ribosomes in cells.

However, the infection did modify the underlying molecular structure of the ribosome, leading to increased poxvirus protein translation. Genetic knockout screens coupled with metabolic assays ...

We showed that non-AUG translation is strikingly resistant to multiple protein synthesis inhibitors, including cycloheximide. We find that these inhibitors slow elongating ribosomes, thereby inducing ...