Rett syndrome is a neurodevelopmental disorder that primarily affects girls, most of whom have mutations in the transcription regulatory gene MECP2. However, mutations in MECP2 also have been ...

Rett syndrome is caused by mutations of the MECP2 gene located on the X chromosome. Children with Rett initially show typical ...

Though Rett syndrome is genetic, it isn't inherited from either parent. Instead, it's caused by a gene mutation. Children ...

Studies in patients with Rett syndrome revealed that mutations are almost exclusively of paternal origin. [29] The mutations in MECP2 are obviously a product of spermatogenesis, because the father ...

Rett syndrome is a devastating neurological disorder caused mainly by mutations in the MECP2 gene found on the X chromosome, so mainly affects females. It causes deficits in brain function that ...

Rett syndrome is a devastating neurological disorder caused mainly by mutations in the MECP2 gene found on the X chromosome. The disease causes deficits in brain function that lead to behavioural ...

In 1999, a decade-long search for the genetic basis for Rett syndrome succeeded in identifying mutations in the MECP2 gene in girls fulfilling the criteria for the syndrome. This discovery allowed ...

Some patients have a mutation in the gene but not the disease. Others may have symptoms of Rett syndrome without the gene mutation. Joining Zoghbi for the Congress will be Dr. Daniel Glaze, professor ...

Taysha Gene Therapies' TSHA-102 tackles Rett syndrome’s root cause with its ... that’s also prevalent in women due to MECP2 gene mutations. This is because this particular gene is only found ...

If granted marketing authorization, trofinetide will be the first and only approved therapy for Rett syndrome in the European Union (EU). Trofinetide is already approved in the United States and ...