The dynamic formation and cleavage of a disulfide linkage between two cysteine amino acid residues has profound importance in cell biology, in particular for redox sensing, allosteric regulation of ...

Background Chronic inflammation and elevated reactive oxygen species are key contributors to hepatocellular carcinoma (HCC) ...

The reduction of a redox-active ligand is shown to drive reversible switching of a Cu(I) [2]pseudorotaxane ([2]PR+) into the reduced [3]pseudorotaxane ([3]PR+) by a bimolecular mechanism. The ...

Targeting the G-loop mechanism could be a smart way to hit cancer cells where they’re weak. For example, by increasing the number of G4 knots or blocking their repair, cancer cells could be killed ...

Kang, Q. and Yang, C. (2020) Oxidative Stress and Diabetic Retinopathy Molecular Mechanisms, Pathogenetic Role and Therapeutic Implications. Redox Biology, 37, Article ID 101799. Login ...

Targeting the G-loop mechanism could be a smart way to hit cancer cells where they’re weak. For example, by increasing the number of G4 knots or blocking their repair, cancer cells could be ...

Tremendous efforts have been devoted to developing chemodynamic cancer therapy (CDT) platforms targeting intracellular antioxidant defense systems to realize an enhanced efficacy. However, such a ...