What can the systems theory distinction between positive and negative feedback tell us about how recovery succeeds?

Background Chronic inflammation and elevated reactive oxygen species are key contributors to hepatocellular carcinoma (HCC) ...

Targeting the G-loop mechanism could be a smart way to hit cancer cells where they’re weak. For example, by increasing the number of G4 knots or blocking their repair, cancer cells could be ...

Cryptochrome is currently the major contender of a protein to underpin magnetoreception, the ability to sense the Earth’s magnetic field. Among various types of cryptochromes, cryptochrome 4 has been ...

It is therefore possible that redox regulation of disulfide bridges may be a widespread mechanism for controlling protein kinase activity and signaling. In a previous study led by Kannan, roughly 10% ...

Impact of T-Loop and CPE Cys-to-Ala mutations on BRSK redox sensitivity in a cellular EGFP-Tau HEK-293T co-expression system. Representative immunoblot of EGFP-Tau co-expressed with WT and Cys-to-Ala ...

The paper entitled, "Redox-stress response resistance (RRR) mediated by hyperoxidation of peroxiredoxin 2 in senescent cells," was published online in Science China Life Sciences.

One such mechanism is the nuclear factor erythroid 2-related factor 2 (NRF2)-mediated stress response, where NRF2 is a master transcription factor that aids in reducing oxidative stress. Much is known ...

One such mechanism is the nuclear factor erythroid 2-related factor 2 (NRF2)-mediated stress response, where NRF2 is a master transcription factor that aids in reducing oxidative stress.

The study, published in the journal Redox Biology, has described - in patients and animal model samples of type 2 diabetes - a decrease in mitochondrial proteins that synthesize complex subunits ...