Kyle Shanahan provided an estimated injury timetable for key players who exited San Francisco's preseason tilt vs. the Las Vegas Raiders.

Injury updates from the preseason matchup between the San Francisco 49ers and Las Vegas Raiders at Allegiant Stadium in Las Vegas.

Multiple preseason injuries created serious questions about San Francisco’s offensive line stability and backfield depth heading into Week 1.

The 49ers played their starters to open Saturday's game against the Raiders, but one member of the group had to leave with an injury.

Puni, a third-round pick of the 49ers last year, played a key role for the team as a rookie. The 25-year-old played a team-high 1,078 offensive snaps, allowing just three sacks, along with 35 pressures and 32 hurries, according to Pro Football Focus.

Raiders running back Ashton Jeanty had fans worried after he left the preseason game against the 49ers with an arm injury.

Las Vegas Raiders' first round pick Ashton Jeanty triggered concern early in their preseason matchup against the San Francisco 49ers, entering the medical tent after sustaining an