In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...

"The different and more complex architecture allows the U11 snRNP to specifically identify its rare substrates in the vast RNA sequence landscape ... needed before the splicing reaction concludes.

EMBL Grenoble Group Leader Wojciech Galej, who has been working on pre-mRNA splicing machinery ... allows the U11 snRNP to specifically identify its rare substrates in the vast RNA sequence ...