Ahn’s study, “SON drives oncogenic RNA splicing in glioblastoma by regulating PTBP1/PTBP2 switching and RBFOX2 activity” was published in Nature Communications. Ahn says that glioblastoma multiforme ...

We have discovered an artificial DNA enzyme that mimics the first step of RNA splicing. In vitro selection was used to identify DNA enzymes that ligate RNA. One of the new DNA enzymes carries out ...

During the first step of converting genetic information into functional proteins, cells transcribe the double-stranded helix ...

A new study reveals that blocking ribosomal RNA production rewires cancer cell behavior and could help treat genetically ...

RNA splicing ribozymes have been shown to possess a conserved active ... “These RNA-binding small molecules selectively inhibit the two steps of splicing by adopting distinctive poses at ...

RNA splicing is an important step in gene expression that takes place in the nucleus of the cell and involves the cutting and joining of RNA segments.

"RNA splicing is an essential step between transcription and translation," said corresponding author Junmin Peng, Ph.D., St. Jude Departments of Structural Biology and Developmental Neurobiology ...

RNA splicing is a process that removes non-coding genetic sequences and joins protein-coding sequences together. "RNA splicing is an essential step in transcription and translation," said ...

RNA-Seq can be used to identify splicing factors or regulatory proteins whose knockdown or inhibition can alter splicing patterns. By silencing the expression of specific splicing factors using siRNAs ...

RNA splicing, a process discovered in the late 1970s, ... In the first step of spliceosome assembly, an snRNA molecule known ...