During the first step of converting genetic information into functional proteins, cells transcribe the double-stranded helix ...

A new study reveals that blocking ribosomal RNA production rewires cancer cell behavior and could help treat genetically ...

News & Views Published: December 2008 Short-circuiting RNA splicing Matthew D Disney Nature Chemical Biology 4, 723–724 (2008) Cite this article ...

Google DeepMind has introduced a new AI tool called AlphaGenome. It reads long stretches of human DNA and predicts ...

Researchers have developed a gene therapy that significantly slowed motor function loss in preclinical models of amyotrophic ...

A team of Indian American scientists led by Pallavi Gopal are working to learn more about the dynamics of a protein to help ...

Professor Hirohide Saito (Department of Life Science Frontiers at CiRA / The University of Tokyo) and Assistant Professor ...

RNA splicing is a modification of the nascent pre-messenger RNA (pre-mRNA) transcript in which introns are removed and exons are joined prior to translation. For many eukaryotic introns, splicing ...

The tumor suppressor p53 is a transcription factor that controls the expression of hundreds of genes. Emerging evidence suggests that the p53-induced RNA-binding protein ZMAT3 is a key splicing ...

Proteins are the infinitely varied chemicals that make cells work, and science has a pretty good idea how they are made. But ...

Our study reveals that the ribosomal protein RPL22, typically a structural component of the ribosome, plays an unexpected dual role as a critical regulator of RNA splicing." ...