Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

RNA splicing, a process discovered in the late 1970s ... allowing the cell to assemble the correct sequence for a desired ...

“Because the binding pocket of the RBP matches the sequence motif, the RBP binds to the specific set of several nucleotides. Then the RNA binding protein ... mediated decay (NMD) is a process closely ...

The pre-mRNA molecule thus goes through a modification process in the nucleus called splicing ... RNA molecule that is then translated into a protein. Introns are also referred to as intervening ...

Scientists at Oak Ridge National Laboratory have developed the first-ever method of detecting ribonucleic acid, or RNA, ...

As its name suggests, splicing involves snipping out certain sequences in the RNA ... introduced during this splicing process. Biogen has been involved in RNA splicing research since its earliest ...

RNA splicing, a process discovered in the late 1970s ... allowing the cell to assemble the correct sequence for a desired ...

which are removed during the process of RNA splicing before the gene is translated into a protein. Genes also contain regulatory sequences, such as promoters and enhancers, which control when and ...

This process is known as splicing. Ultimately, the spliced messenger RNA consists of only protein-encoding exons. Splicing is catalyzed by a large molecular machine. This spliceosome is made up of ...

RNA (ribonucleic ... nucleotide bases. Trans-splicing enables the ligation of exons from different pre-mRNAs into a single transcript. A recent study harnesses this process and develops ...

Alternative RNA splicing is similar to a movie editor cutting and rearranging scenes from the same video to produce distinct versions of a film. By deciding which sequences to keep and which to ...