Biochemists Uncover How Cells Eliminate RNA Splicing Errors
Heidelberg biochemists and structural biologists from Shanghai unravel the roles of two key regulatory factors in mRNA ...
EMBO Press1d
CD47-amyloid-β-CD74 signaling triggers adaptive immunosuppression in sepsis
CD47-amyloid-β-CD74 signaling is a key driver of adaptive immunosuppression in sepsis, suppressing B cells and impairing ...
This RNA Twist Could Rewrite What We Know About “Self” and “Nonself”
Scientists found that pseudouridine helps small RNAs pass on traits and avoid immune detection, offering clues for future RNA ...
Fluorescent biosensor tracks plant RNA in real time for better crops and biosecurity
Scientists at Oak Ridge National Laboratory have developed the first-ever method of detecting ribonucleic acid, or RNA, ...
eLife16d
Generative modeling for RNA splicing predictions and design
BO is an iterative, model-based optimization procedure involving the use of a surrogate model (typically a Gaussian Process, or GP ... of this study is the formulation of RNA sequence design with ...
Frontiers17d
Identified five variants in CFTR gene that alter RNA splicing by minigene assay
Emerging evidence suggests that some variants, which are described as missense, synonymous or nonsense variants in the literature or databases, may be deleterious by affecting the pre-mRNA splicing ...
Nature18d
RNA quality control articles from across Nature Portfolio
RNA quality control is the active process by which ribonucleic acid ... and TENT5A/C substrate mRNAs are highlighted in the paper. Proper splicing requires efficient spliceosome assembly.
Hindustan Times18d
New study reveals a simple genetic approach to tackle aggressive cancers
Alternative RNA splicing is similar to a movie editor cutting and rearranging scenes from the same video to produce distinct versions of a film. By deciding which sequences to keep and which to ...