Biochemists Uncover How Cells Eliminate RNA Splicing Errors
Heidelberg biochemists and structural biologists from Shanghai unravel the roles of two key regulatory factors in mRNA ...
This RNA Twist Could Rewrite What We Know About “Self” and “Nonself”
Scientists found that pseudouridine helps small RNAs pass on traits and avoid immune detection, offering clues for future RNA ...
Fluorescent biosensor tracks plant RNA in real time for better crops and biosecurity
Scientists at Oak Ridge National Laboratory have developed the first-ever method of detecting ribonucleic acid, or RNA, ...
eLife17d
Generative modeling for RNA splicing predictions and design
as it offers both a refined predictive model and a new tool to designing RNA sequences for targeted splicing outcomes. Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific ...
eLife17d
Generative modeling for RNA splicing predictions and design
The authors propose a transformer-based model for the prediction of condition - or tissue-specific alternative splicing and demonstrate its utility in the design of RNAs with desired splicing outcomes ...
Frontiers18d
Identified five variants in CFTR gene that alter RNA splicing by minigene assay
Emerging evidence suggests that some variants, which are described as missense, synonymous or nonsense variants in the literature or databases, may be deleterious by affecting the pre-mRNA splicing ...
C&EN25d
Phosphorylation-Induced Self-Coacervation versus RNA-Assisted Complex Coacervation of Tau Proteins
Institute of Biological Chemistry, Academia Sinica, No. 128, Sec. 2, Academia Road, Nankang, Taipei 115, Taiwan Institute of Biochemical Sciences, National Taiwan ...