In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

Cambridge, Massachusetts-based Envisagenics focuses on using AI to analyse errors in RNA splicing, a process in which a precursor form of messenger RNA (mRNA) – which is used as a template for ...

Splicing is a basic requirement for producing proteins that ... they are first copied into precursors of mRNA, or messenger ...

Specific RNA Sequences Are Required for Regulation of Alternative Splicing If we want to understand the splice code, then we need to analyze the existing information about constitutive and ...

RBP splicing factors are sequence-specific, binding to their cognate sequence motifs like a lock and key. “Because the binding pocket of the RBP matches the sequence motif, the RBP binds to the ...

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Alternative splicing (AS), a critical process for gene expression regulation, allows a single precursor ...

UMD researchers have discovered key mechanisms in gene regulation that could improve the design of RNA-based medicines.

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...

In this webinar, Dr. Megan L Noonan will present her research on the role of alternative splicing in kidney disease progression, discussing how she used nanopore RNA sequencing to accurately detect ...

Splicing is a basic requirement for producing ... they are first copied into precursors of mRNA, or messenger RNA. The spliceosome then converts them into mature, functional mRNA.