Nutrition scientists have been working to understand the relationship between type 2 diabetes and genes that express a ...

Cold sore-causing HSV-1 doesn't just hijack cells it reconfigures the entire architecture of our DNA to aid its invasion.

Viruses are entirely dependent on their hosts to reproduce. They ransack living cells for parts and energy and hijack the ...

Viruses are entirely dependent on their hosts to reproduce. They ransack living cells for parts and energy and hijack the ...

The new study, funded in part by the National Institutes of Health and published June 18 in Cell Chemical Biology, showed that targeting a key process of how cells make proteins can inhibit cancer ...

Eli Lilly has put up to $1.3 billion on the line to partner with South Korea’s Rznomics and gain access to the biotech’s novel RNA editors for hearing loss. Aside from the total deal value, details of ...

Here, we used Single-Molecule Footprinting to measure RNA Polymerase II (Pol II) occupancy, the fraction of DNA molecules bound, at promoters in mouse and Drosophila cell lines. Single-molecule data ...

Le Martelot G, Canella D, Symul L, Migliavacca E, Gilardi F, Liechti R, Martin O, Harshman K, Delorenzi M, Desvergne B, et al. Genome-wide RNA polymerase II profiles and RNA accumulation reveal ...

The RNA polymerase II (Pol II) elongation rate influences poly (A) site selection, with slow and fast Pol II derivatives causing upstream and downstream shifts, respectively, in poly (A) site ...

RNA polymerase II 3 transcribes protein-coding genes into messenger RNA (mRNA). This 12-subunit enzyme works as a complex that directly influences gene expression through its production of pre-mRNA ...

The C-terminal domain (CTD) of RNA polymerase II (Pol II) is a low complexity domain that contains heptapeptide (YSPTSPS) repeating sequence, with the number of repeating units differing according to ...

Glioblastoma multiforme (GBM) is the most common and aggressive brain tumor with a poor prognosis. The growth of GBM cells depends on the core transcriptional apparatus, thus rendering RNA polymerase ...