Transcription termination is one of the least-understood processes in gene expression. However, recent studies have revealed common themes and principles between models of RNA polymerase II (Pol ...

How RNA Polymerase II Gets The Go-ahead For Gene Transcription Date: October 9, 2009 Source: Ludwig-Maximilians-Universität München Summary: The central dogma of molecular biology states that ...

Transcription of eukaryotic protein-coding genes is initiated by RNA polymerase II (Pol II) in a complex with transcription factors including the transcription factor IIB (B). The crystal ...

RNA polymerase II also produces micro RNA (miRNA) molecules. These non-coding transcripts can mediate gene expression and the activity of mRNAs after transcription.

An RNA polymerase II molecule is about 15 nanometers across, or roughly 5,000 times smaller than the width of a human hair. This image was created by reconstructing X-ray diffraction crystallography ...

New study shows RNA polymerase I halts at abasic DNA damage, helping prevent faulty rRNA production and exposing lesions for repair in dividing cells.

A cold sore might seem like a minor nuisance. But behind that tingling lip is one of the world’s most widespread and cunning viruses—herpes simplex virus type 1, or HSV-1. It infects billions of ...

Scientists have recently uncovered the mechanisms of how RNA polymerase II performs intrinsic cleavage reaction to proofread RNA transcriptions, shedding light on how misregulation of accurate ...

The researchers found that using a drug to inhibit RNA Polymerase 1 (Pol 1) - the enzyme responsible for human ribosomal RNA (rRNA) transcription - triggered a unique stress response that rewires ...

The transcription of ribosomal RNA by RNA Polymerase I (Pol I) is an essential step for cells to grow and thus is considered a therapeutic target for cancer treatment.

This article describes the three types of RNA polymerase (RNAP), the enzyme responsible for transcription in eukaryotic cells.

RNA polymerase II 3 transcribes protein-coding genes into messenger RNA (mRNA). This 12-subunit enzyme works as a complex that directly influences gene expression through its production of pre-mRNA ...