Researchers at Case Western Reserve University have discovered molecules that present the potential to drive the development ...

POLG-related diseases disrupt the function of the mitochondria, or "powerhouses" of the cell — starving them of energy.

Japan-based Ono Pharmaceuticals has secured the global rights to sapablursen, an RNA-targeting therapy developed by Ionis ...

Ionis’ drug, called sapablursen, is currently being tested in a Phase 2 trial in people with polycythemia vera.

Ionis Pharmaceuticals IONS signed a license agreement with Japan-based Ono Pharmaceutical. Per the terms, Ono has acquired exclusive global rights from IONS to develop and market sapablursen, an ...

Japan's Ono Pharmaceutical is handing over $280 million upfront to acquire Ionis Pharmaceuticals’ phase 2-stage antisense ...

This month's cover highlights the article Immune cells adapt to confined environments in vivo to optimise nuclear plasticity for migration by Helen Weavers and Tua Karling. The cover features confocal ...

Type 1 diabetes occurs when the immune system attacks pancreatic beta cells. Type 2 diabetes happens when the body cannot use insulin effectively. The two types differ in symptoms, causes ...

Body Dimensions 145 x 70.4 x 8.6 mm (5.71 x 2.77 x 0.34 in) ...

WASHINGTON, DC — Jordan Bardella, the telegenic leader of the National Rally, says he’s been fighting for the “soul” of France since he dropped out of university to work full time for the ...

An experimental approach to treating pancreatic cancer with the messenger RNA (mRNA)-based therapeutic cancer vaccine ... New results from the phase 1 clinical trial, now published in the journal ...

Darnell discovered that when they put this exclusively human variant of NOVA1-an RNA-binding protein in the brain known to be crucial to neural development-into mice, it altered their ...