Mitochondrial deoxyribonucleic acid (mtDNA) is essential for cellular energy production and overall cell function.

Get Instant Summarized Text (Gist) A computational tool named NuFold has been developed to model 3D RNA structures, potentially accelerating medical discoveries by decades. This tool addresses the ...

Darnell discovered that when they put this exclusively human variant of NOVA1 -- an RNA-binding protein in the brain known to be crucial to neural development -- into mice, it altered their ...

The researchers visualized translation, including ribosome pauses, by using the intensity of GFP-tagged antibodies on the polypeptide to measure polypeptide elongation ... repetitive sequences and ...

Advances in genomic technologies have enabled the discovery of novel functions for TOP2B in processes such as releasing of the paused RNA polymerase II and maintaining ... directly by acting on ...

In upland cotton, the identification of key genes involved in fiber elongation and secondary cell wall biosynthesis has enabled researchers to develop molecular markers for improving fiber quality and ...

There, he’d defrost small vials of lung cancer specimens from the lab’s deep freezer and extract a single microgram of RNA from each tube. Some of the specimens came from people whose cancers ...

Here, we present two cryo-EM structures of the SecM-stalled ribosomes at 3.3–3.7 Å resolution, which reveal two different stalling mechanisms at distinct elongation steps of ... residence of the ...

Production of mRNA depends critically on the rate of RNA polymerase II (Pol II) elongation. To dissect Pol II dynamics in mouse ES cells, we inhibited Pol II transcription at either initiation or ...