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The spliceosome is a complex ribonucleoprotein machine that is responsible for the maturation of cellular pre-mRNAs by removing introns and ligating together the surrounding coding regions, called ...
The European Molecular Biology Laboratory (EMBL) is Europe's esteemed lab network for research in molecular biology. EMBL is funded by 20 member states an one associate member. EMBL operates in 5 ...
Ten Indian American scientists were honored for their outstanding contributions in cancer research by the (SAASCR).
A new strategy of belief propagation (BP) decoder for LDPC codes is presented by sequentially concatenating the scheduling algorithms of flooding and node-wise residual belief propagation (NW RBP) ...
KEGG analysis of the upregulated genes revealed enrichment in pathways including spliceosome, oxidative phosphorylation, peroxisome activity, cytochrome P450, proteasome, and thiamine ...
The DExH‐box NTPase/helicase Prp22p plays two important roles in pre‐mRNA splicing. It promotes the second transesterification reaction and then catalyzes the ATP‐dependent release of mature mRNA from ...
Sudemycin K, a derivative that replaces the pharmacophore’s oxycarbonyl by an amide group, displays improved potency as an inhibitor of cancer cell proliferation, as a regulator of alternative ...
NB in the high-E2F group presented increased activity in the spliceosome, ATP-dependent chromatin remodeling, and other pathways related to genome regulation (Figures 7A, B). To analyze the tumor ...