The data convincingly show that the transcription factor Sp1 regulates ephrin-mediated axon guidance in the spinal cord. Although the authors show that Sp1 and its co-activators p300 and CBP are ...

A significant discovery has identified a missing "gatekeeper" protein as the root cause of dry mouth in Sjögren's syndrome — ...

New research has uncovered more about the complexity of human gene regulation by identifying certain sequences of proteins ...

Research into transcription factors deepen understanding of the 'language' of the genome, offering insights into human development.

Neuroscientists have produced the largest wiring diagram and functional map of a mammalian brain to date using tissue from a ...

How chromatin openness controls behavioral changes remains unclear. This work implicates alternative promoter selection, ...

A team of CiRA researchers has uncovered the crucial role of EIF3D—a protein translational regulator—in primed pluripotency.

The launch of the ElevenLabs Model Context Protocol (MCP) server on GitHub marks a significant advancement in audio ...

Researchers say they have mapped more than 200,000 cells in a cubic millimeter of brain tissue and have traced how they're all connected.

The 3D brain map includes more than 200,000 cells, 523 million synapses and over two miles of axons, representing the most detailed wiring diagram of a piece of mammal brain ever constructed ...

Transcription is the process by which an RNA polymerase synthesizes ribonucleic acid (RNA) using deoxyribonucleic acid (DNA) as a template. In this Perspective, the authors propose that ...

However, the evidence supporting some of the conclusions remains incomplete, and further mechanistic studies are needed to clarify how miR-283 affects normal aging and influences exercise adaptations.