Carboxylic acids have been shown to be good phosphate bioisosteres (Burke and Lee, 2003; Elliott et al., 2012). Yet phosphonic acids could potentially better-replicate cognate TOP1-DNA substrate ...

Parkinson’s disease (PD), a long-term and complex movement disorder, is hallmarked by the classical motor features, including slowness of movement, resting tremors, stiffness, and postural instability ...

She has 15+ years of experience as a financial writer and technical analyst. A firm's capital structure is a mix of borrowed money and investor funding that it uses to fund itself. When Meta ...