Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results from a combination of higher Pol II turnover and lower transcription ...

To implement the blueprint it contains, RNA polymerase is used. The enzyme reads the information stored in the template and makes the corresponding RNA component. Algorithms specifically developed ...

Introduction: RNA polymerase III (Pol III) is a critical enzymatic complex ... natural history study of Bluebird Bio (2019), a site sub-investigator for the MPS II gene therapy trial of Regenxbio ...

“What’s striking about this study is that this gene, tamas, encodes a subunit of the mitochondrial DNA polymerase, which is the enzyme ... specifically when the mtDNA is being degraded during ...

These messenger RNAs are then used as templates for protein production. In animals, plants and other eukaryotic organisms, an enzyme called RNA polymerase II is responsible for making messenger RNA ...

We have performed ChIP-seq experiments on tightly staged Drosophila embryos and show that massive recruitment of RNA polymerase II (Pol II) with widespread pausing occurs de novo during the ...