Myeloid deficiency of the mitochondrial transacetylase tafazzin upregulates mtROS, disrupting UPR and calcium homeostasis, ...

Recent studies have highlighted the functional capacity of neutrophils as powerful mediators of tissue inflammation. Granule-packaged proteases and reactive oxygen intermediates, which are ...

This cluster displayed unique characteristics, including fewer specific granules and a lower maturity score compared to other neutrophil types, suggesting a specialized role in AD pathology.

These granules are released upon encountering potential ... the team discovered a surprising interaction: neutrophils were found inside mast cells. "We could hardly believe our eyes: living ...

found that mice made deficient in neutrophil-granule proteases but with normal superoxide production and io Reeves et al. found that mice made deficient in neutrophil-granule proteases but with normal ...