The more recently solved 3D structures of the PCAF and CBP bromodomains bound to lysine-acetylated histone H3 and H4 peptides provide important new insights into the structural and molecular bases ...

These incisive chemical probes have availed new insights into chromatin structure and function, and suggest plausible translational opportunities for the targeted development of drug-like derivatives ...

The most recently discovered amino acid, pyrrolysine, is produced by a series of just three chemical reactions with a single precursor -- the amino acid lysine, according to new research.

The collagen molecule, also known as the “tropocollagen”, is part of larger collagen aggregates such as fibrils. The whole molecule is approximately 300 nm long and 1.5 nm in diameter.

Proteins are formed in cells by linking amino acid building blocks together in a defined sequence. There are 20 different amino acids that are used to build proteins, including cysteine and lysine ...

Researchers have long known that glycosaminoglycan-binding proteins (HBPs) help control vital processes like cell growth, inflammation, and blood clotting. But a recent discovery has revealed a hidden ...

Dublin, April 22, 2024 (GLOBE NEWSWIRE) -- The "Lysine specific demethylase 1 inhibitors - Pipeline Insight, 2024" clinical trials has been added to ResearchAndMarkets.com's offering.This "Lysine ...

Using cryo-electron microscopy, which enables visualization of frozen molecular structures at high resolution, the team analyzed this unique complex at a resolution of 3.66 Å ...

New technology which is capable of profiling RNA structure at the resolution of a single molecule in live cells. Credit: John Innes Centre. Download Article Listen with Speechify 0:00 ... But it was ...

A team of researchers at the University of California, Davis, made small tweaks to the molecular structure of lysergic acid diethylamide (LSD) to see if it could be turned into an effective brain ...

As a small molecule, Structure’s lead drug candidate is less expensive to make and easier for patients to take as a once-daily pill. A Phase 1 test of GSBR-1290 in healthy volunteers was ...